Friday, October 25, 2013

Berlusconi party risks split that could imperil Italy's coalition


By Roberto Landucci


ROME (Reuters) - Moderates in Silvio Berlusconi's center-right movement pulled out of a leadership meeting on Friday, risking a split that could threaten the stability of Italian Prime Minister Enrico Letta's coalition.


The wrangling within Berlusconi's People of Freedom (PDL) party may further damage already weak coalition cohesion on policy, hobbling efforts to reform a sclerotic economy - the euro zone's third largest - stuck in a two-year-long recession.


The PDL has come close to breaking up over growing tension between hardliners pressing for a break with Letta's shaky bloc of left and right and a moderate group that backs the government formed in the wake of February's inconclusive election.


After an angry meeting between Berlusconi and party secretary Angelino Alfano, the so-called "doves" including the five PDL ministers in the government decided to boycott a meeting of the party leadership group, led by Berlusconi.


"My contribution to the unity of our political movement, which I will never block for reasons to do with my personal role, is not to take part, along with other colleagues in the presidium meeting," Alfano said in a statement.


The divisions emerged clearly this month when moderates led by Alfano defied orders and backed Letta in a confidence vote in parliament, humiliating Berlusconi and forcing him to abandon an attempt to bring down the government.


Whether a split in the center-right would unravel the government was not clear but it appears likely to raise tension between the PDL and Letta's center-left Democratic Party (PD), and further dim prospects of any sustained economic reform.


The problems have been exacerbated by Berlusconi's impending expulsion from parliament over a tax fraud conviction, which will have to be approved by a vote in the Senate and which could expose him to the risk of arrest in other criminal cases.


The PDL leadership was to meet on Friday to discuss changing the name of the party to Forza Italia, as Berlusconi's original movement was known when the billionaire media magnate, now 77, entered politics in 1994.


Members of the moderate faction regard such a change, which could see Alfano's position as party secretary abolished, as a way of reinforcing the influence of the conservative hardliners and had called for the meeting to be postponed.


"There can be a frank, honest and open debate, that's one thing," said Roberto Formigoni, a former governor of the affluent northern Lombardy region who broke with Berlusconi and supported the government in the October 2 confidence vote.


"But if the PDL wants to take an extremist line which isn't part of our story, perhaps by changing into Forza Italia - trying to smash everything to save who knows what but actually sinking the country, we can't go along with that," he told SkyTG24 television.


The PDL infighting arose with parliament preparing to debate a 2014 budget law that has been widely criticized for failing to cut taxes enough and doing little to reduce wasteful spending.


(Editing by Mark Heinrich)

Source: http://news.yahoo.com/berlusconi-party-risks-split-could-imperil-italys-coalition-170007721--business.html
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Pokemon X (for Nintendo 3DS)


Pokemon's back. Of course it's back—it's one of Nintendo's biggest cash cows. Every few years we see a new Pokemon generation that includes over a hundred new Pokemon, a handful of older ones, and the exact same formula of the previous games. This time the generation is Pokemon X and Y for the Nintendo 3DS. Yes, it's formulaic. Yes, it hits all the same notes as previous Pokemon games. Yes, it's barely changed mechanically. But you know what? A great series doesn't have to change much, and Pokemon X/Y are must-buy titles (well, title; you don't need both) for $39.99 (direct). This is the best-looking Pokemon game yet; it makes your Pokemon battles actually look like the anime. So what if not much else has changed?


Editors' Note: This review is based on a playthrough of Pokemon X. Pokemon Y is effectively identical, except for some of the Pokemon available.


3D Makeover
Pokemon were barely animated sprites in the main titles for over a decade, and now they're cel-shaded, 3D characters that come to life on the screen. The Pokemon look and move like they're from the anime, a far cry from the sprites of previous games, and while attack animations and effects are still limited and often just appear as waves of particle effects, there there's enough variety in animation and action to make Pokemon battles actually seem like battles from the anime and not just two pictures of Pokemon shaking at each other. This is a massive upgrade over earlier Pokemon games, and a welcome change.




The overworld is rendered in 3D (though strangely not displayed in 3D on the 3DS screen) like in Pokemon Black/White and Black/White 2, and it generally looks very good as well except for a few frustrating camera issues. The 3D camera tends to get cinematic in certain caves and in Luminoise City, the large hub city in the Kalos region, and it can make navigation much more disorienting than if it was the more conventional top-down view used in other towns and open areas. If you want to navigate Luminoise City, it's easier to spend the 1,000-odd Pokebucks and hire a cab to take you where you want to go.


Sound didn't get nearly as much of an upgrade as the graphics, but it did see a notable change with the series' mascot. Nearly every Pokemon has the same type of synthesized growl, scream, or shout as every Pokemon in every previous game has, but Pikachu (which you can now catch easily and early on Route 3) is now voiced with the same cute "Pika!" sounds it makes in the American dub of the anime. It's small, but adorable. Like Pikachu.


Mechanics
Combat is nearly the same as every other Pokemon game. Your Pokemon has four moves of different types based on its own type (Normal, Fighting, Psychic, Fire, and others) and a handful of other characteristics and abilities that determine how it fights. You take turns with other trainers or wild Pokemon to make the opponent faint or weaken a wild Pokemon enough to catch it. If you've played a Pokemon game before, you know what to expect.


Pokemon X/UTwo significant changes to the mechanics can shift how you play, and a few other tweaks give the game more variety. There's now an additional Pokemon type, Fairy, which further complicates the elemental rock-paper-scissors strategy at the core of the game. You can also temporarily evolve some of your Pokemon with Mega Evolutions that give them Super Saiyajin (or, if you prefer, Digivolved) forms that enhance their stats for a fight. These forms require special Mega Evolution stones you have to hunt for, and not all Pokemon can Mega Evolve. There are also Horde battles with wild Pokemon, where one of your Pokemon is surrounded by five weaker wild Pokemon and has to attack them one at a time or use certain skills that affect all other Pokemon to hit them.


Pokemon X/Y gets started faster and makes things easier than in previous Pokemon games. To start, you get your starter Pokemon, Pokeballs, and Roller Skates (the equivalent to Running Shoes) almost immediately and before you even meet Professor Sycamore, the Pokemon Professor of the Kalos region. There are fewer and faster tutorials, which means experienced Pokemon players can jump in much quicker. You also get the Exp. Share item early, and it's much easier and simpler to use than in earlier games. Instead of a held item that splits the experience you win between the active Pokemon and the Pokemon holding the item, it's a key item you can toggle on and off that splits experience between the active Pokemon and all other Pokemon in your party. This means you can level up other Pokemon besides your main ones much faster and you don't have to juggle items between them.


Pokemon X/YThe story is minimal and almost identical to every other main Pokemon series game. You wander around a region (in this case, the France-inspired Kalos region), battle through eight Gyms and defeat the Gym Leaders to get badges, fight the Elite Four and the Champion at the Pokemon League, and while you do it thwart the plans of a nefarious Team that wants to destroy the world and rebuild it. This time, your criminal organization of the generation is Team Flare, but you can feel free to call them Team Failure. They're silly at best and downright stupid at worst, and the pseudo-philosophy of their evil plan seems so tacked on and random that two criminals chasing a ten-year-old for years to get his fairly common Pokemon makes more sense. You don't play Pokemon for the story.


What to Do
It's easy to get distracted catching Pokemon, and there are plenty of non-story activities you can enjoy while playing the game. The new Super Training and Pokemon-Aime menus let you play minigames and respectively train your Pokemons' stats and happiness anywhere you are. You can't show off your Pokemon in contests anymore, but you can make promotional videos of yourself as a trainer, work in hotels, sit in cafes and see rare Pokemon, and perform battles, trades, and other activities to get items.


After you've beaten the Elite Four, there are still plenty of things to do in the Kalos region. You can find several legendary Pokemon in addition to the main game legendary Pokemon (Xerneas for X, Yvetrai for Y), and another town is unlocked where you can use the Battle Maison and Friend Safari. The Battle Maison is like the post-game battle settings in previous Pokemon games, where you can form teams of three non-Legendary Pokemon de-leveled to 50 for each match and have a purely strategic endurance run against other trainers. Friend Safari lets you collect rare Pokemon based on your Friend Codes. Each friend you register becomes a different safari where you walk around a small patch of grass and catch up to three Pokemon, depending on if they beat the game and have been online when you are online at least once (otherwise there are only two). The Friend Safari Pokemon include some highly sought after Pokemon, including the first and sixth generation starters, Ditto (useful for breeding), and several Ghost and Dragon-type Pokemon you wouldn't be able to catch otherwise.


Online options are of course plentiful. You can trade and duel with people online if you exchange Friend Codes or locally, and Friend Safari makes Friend Code collecting surprisingly addictive. You can send messages to each other and even give special O-Powers that give temporary boosts to yourself or other trainers. You can't trade Pokemon from the previous generation to this one, but that feature will be offered in December when Nintendo launches the Pokemon Bank and Poke Transport services.


Pokemon X/Y doesn't change much besides graphics because it really doesn't have to. The Pokemon formula still holds up as fun, accessible turn-based RPG that focuses on collecting more than story. The graphical updates in combat are great, finally giving Pokemon the action and animation they've needed for over a decade. There aren't many surprises in the game and the addition of the Fairy type doesn't change the mechanics in any noticeable way, but it's still one of the best games on the 3DS. It's simply enjoyable.


Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/uai-pUJq7i4/0,2817,2426268,00.asp
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Visualized: global DDoS attacks animated and mapped by Google

Earlier today, Google announced it had built Project Shield to help small websites stay online during DDoS (distributed denial of service) strikes, and it turns out the search giant also unveiled a frequently-updated online map of such assaults. Dubbed Digital Attack Map, the project was created in ...


Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/xV1sgbDNzgw/
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EXCLUSIVE! The CW Lets Seksi Reign Over Mary, Queen of Scots' Kingdom! Watch The Crazy Preview NOW!



| Filed under: TV News



Hot damn, Mary, Queen of Scots!


You've put yourself into an exceptionally sticky situation—and we're not talking about the masturbation scene that was cut from the pilot! LOLz!


Reign—which airs its second episode TONIGHT, focuses on 15-year-old Mary (played by Adelaide Kane) who has just been freed from a battle between Scotland and England over her crown!


For her safety, she's sent to France to marry the next king, but just wants to have fun, despite the essential curse of the monarchy!


Ch-ch-check out the crazy clip (above) to see if the show's juicy enough for you to tune in!


If you're into love triangles, fancy period clothing, and lavish social events, allow Reign to take over your TV every Thursday on the CW!


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Source: http://perezhilton.com/2013-10-24-exclusive-cw-reign-mary-queen-of-scots-kingdom-watch-clip-now
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New research on innovative ways to prevent, treat childhood obesity presented at AAP conference

New research on innovative ways to prevent, treat childhood obesity presented at AAP conference


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25-Oct-2013



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Contact: Debbie Jacobson
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American Academy of Pediatrics





ORLANDO, Fla. -- A special session at the 2013 American Academy of Pediatrics (AAP) National Conference & Exhibition in Orlando will highlight innovative, successful ways pediatricians are working to prevent and treat childhood obesity.

The session, from 8 to 11 a.m. Friday, Oct. 25, at the Orange County Convention Center, is hosted by the AAP Institute for Healthy Childhood Weight, which was founded in 2012 to lead the academy's efforts in providing pediatricians, families and communities with evidence-based resources to help prevent and treat childhood obesity.

Friday's session will showcase work being done by AAP chapters and member pediatricians to prevent and treat childhood obesity. After a competitive abstract submission process, six abstracts were chosen for oral presentation and 17 were accepted as posters.

"We are excited to provide this venue to elevate the great work of our members and chapters," said Sandra Hassink, MD, FAAP, chair of the Institute for Healthy Childhood Weight advisory board. "Our hope is to think critically about these innovations and identify where we as the Institute for Healthy Childhood Weight of the American Academy of Pediatrics can try to spread the innovation more broadly."

Poster presentations begin at 8 a.m. , and will focus on innovative approaches to obesity prevention, assessment and treatment that have promising or proven results. Poster abstracts are available for journalists to review while under embargo at https://aap.confex.com/aap/2013/webprogrampress/Session1947.html

At 9 a.m., researchers will present abstracts on primary care interventions to childhood obesity, followed by abstracts on state and national approaches. A full list of speakers and the text of abstracts selected for oral presentations are available for journalists to review while under embargo at https://aap.confex.com/aap/2013/webprogrampress/Session1946.html

The abstracts are embargoed until 12:01 a.m. ET on Oct. 25.

###


The American Academy of Pediatrics is an organization of 60,000 primary care pediatricians, pediatric medical subspecialists and pediatric surgical specialists dedicated to the health, safety and well being of infants, children, adolescents and young adults. For more information, visit http://www.aap.org.




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New research on innovative ways to prevent, treat childhood obesity presented at AAP conference


[ Back to EurekAlert! ]

PUBLIC RELEASE DATE:

25-Oct-2013



[


| E-mail

]


Share Share

Contact: Debbie Jacobson
djacobson@aap.org
847-434-7084
American Academy of Pediatrics





ORLANDO, Fla. -- A special session at the 2013 American Academy of Pediatrics (AAP) National Conference & Exhibition in Orlando will highlight innovative, successful ways pediatricians are working to prevent and treat childhood obesity.

The session, from 8 to 11 a.m. Friday, Oct. 25, at the Orange County Convention Center, is hosted by the AAP Institute for Healthy Childhood Weight, which was founded in 2012 to lead the academy's efforts in providing pediatricians, families and communities with evidence-based resources to help prevent and treat childhood obesity.

Friday's session will showcase work being done by AAP chapters and member pediatricians to prevent and treat childhood obesity. After a competitive abstract submission process, six abstracts were chosen for oral presentation and 17 were accepted as posters.

"We are excited to provide this venue to elevate the great work of our members and chapters," said Sandra Hassink, MD, FAAP, chair of the Institute for Healthy Childhood Weight advisory board. "Our hope is to think critically about these innovations and identify where we as the Institute for Healthy Childhood Weight of the American Academy of Pediatrics can try to spread the innovation more broadly."

Poster presentations begin at 8 a.m. , and will focus on innovative approaches to obesity prevention, assessment and treatment that have promising or proven results. Poster abstracts are available for journalists to review while under embargo at https://aap.confex.com/aap/2013/webprogrampress/Session1947.html

At 9 a.m., researchers will present abstracts on primary care interventions to childhood obesity, followed by abstracts on state and national approaches. A full list of speakers and the text of abstracts selected for oral presentations are available for journalists to review while under embargo at https://aap.confex.com/aap/2013/webprogrampress/Session1946.html

The abstracts are embargoed until 12:01 a.m. ET on Oct. 25.

###


The American Academy of Pediatrics is an organization of 60,000 primary care pediatricians, pediatric medical subspecialists and pediatric surgical specialists dedicated to the health, safety and well being of infants, children, adolescents and young adults. For more information, visit http://www.aap.org.




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Source: http://www.eurekalert.org/pub_releases/2013-10/aaop-nro102113.php
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Jamie Lynn Spears Shares Adorable Picture of Daughter Maddie, 5, and Fiance -- See What Her Family Looks Like Now


Way back in Dec. 2007, Jamie Lynn Spears was at the center of the media's spotlight when the former Nickelodeon star (and Britney Spears' little sister) announced that she was pregnant at the age of 16. At the time she was starring in the kid's show Zoey 101, and the pregnancy came as a big shock to many fans. 


PHOTOS: Celebrity siblings


Now, almost six years later, Spears, 21, has stepped out of the spotlight to spend lots of time with her little girl, Maddie, who is now 5. And in March 2013 she announced that she was engaged to boyfriend of three years Jamie Watson


PHOTOS: Young Hollywood moms


Jamie Lynn Spears' daughter Maddie, 5, eats ice cream with her fiancé, Jamie Watson, on Oct. 24, 2013.

Jamie Lynn Spears' daughter Maddie, 5, eats ice cream with her fiancé, Jamie Watson, on Oct. 24, 2013.
Credit: courtesy of Jamie Lynn Spears



On Oct. 24, she posted a picture of Watson, 30, eating ice cream with Maddie and captioned it, "I love these 2 more then words can say! Blessed to have such a good man, puppy, and baby girl!!#havingamoment #countingblessings."


Spears was previously engaged to Maddie's father, Casey Alridge, but they called off their engagement in 2009 and officially ended their relationship in 2010. 


PHOTOS: Quickest celebrity engagements ever


The Louisiana native currently lives in Nashville, Tenn. where she is said to be working on a country music career. Her famous older sister, Britney Spears, recently released the hit single, "Work B*tch" and her eighth album, Britney Jean, comes out on Dec. 3. 


Source: http://www.usmagazine.com/celebrity-news/news/jamie-lynn-spears-shares-adorable-picture-of-daughter-maddie-5-and-fiance----see-what-her-family-looks-like-now-20132410
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JBL's Pulse speaker lets you program an LED light show for when your disco needs you

Remember when you first used iTunes and you'd turn on the visualizer, and just stare at the screen as the psychedelic patterns pulsed to the music? Yeah, well no one does that anymore. But since the dream of the '90s is back (it is, right?), JBL's letting music lovers install a bit of the dancefloor ...


Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/LyHbSX1sYLo/
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News Stories Dredge Up Old Stereotypes Of Europe's Roma


Melissa Block speaks with Dr. Jennifer G. Illuzzi, assistant professor of history at Providence College in Rhode Island, about the history of discrimination of the Romani population in Europe following two cases of children who were taken from Roma families into police custody this week in Ireland and Greece.



Copyright © 2013 NPR. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.


AUDIE CORNISH, HOST:


It's ALL THINGS CONSIDERED from NPR News. I'm Audie Cornish.


MELISSA BLOCK, HOST:


And I'm Melissa Block.


There's been a spate of stories from Europe recently involving allegations of child abduction among the Roma people, often referred to as gypsies. In Greece, authorities detained a Roma couple, then took custody of a blonde, fair-skinned, young girl who looked nothing like them. Later, DNA tests showed she is not their daughter. Publicity around that case led to tip-offs in other countries. In Ireland, two young, blond-haired, blue-eyed children who were taken from their Roma parents have now been returned. DNA tests showed the children are theirs.


Well, Jennifer Illuzzi is an assistant professor of history at Providence College in Rhode Island. Her research focuses on the Roma people, and she joins us to provide some perspective on these cases. Professor Illuzzi, welcome to the program.


DR. JENNIFER ILLUZZI: Thank you for having me.


BLOCK: Let's start with this idea that gypsies will steal your children, that they're child snatchers, which seems to be among the most common stereotypes of the Roma people.


ILLUZZI: Yes. There is a long history of the attitude that gypsies are child stealers. And there is this sense that, starting in my own research, in the 19th century, we see many stories of supposed kidnappings by, quote, unquote, "gypsies." And oftentimes, a few days later, a paper will publish a retraction, stating that, in fact, the child had run away from home, the child had wanted to go on an adventure and had left home, the child had been returned home safely.


BLOCK: So where does it originate? Where does this idea come from?


ILLUZZI: If we look back historically, we can associate it, in some ways, with the idea of blood libel, which is a common anti-Semitic trope of Jews stealing children to use them in ritual sacrifices. There is a sense that outsiders are a threat to the culture and the society and the unity of a people. And one of the ways in which they might be thought of as attacking those people is by stealing children and using them for ritual purposes.


BLOCK: Let's talk a bit about the history of the Roma people in Europe. The Roma came from India, arrived in Europe as far back as the 14th, 15th century. And their history there has always been marked by discrimination and persecution, right?


ILLUZZI: Yes. Roma were enslaved in Moldavia and Wallachia, in what is today Eastern Europe and Romania, up until the middle of the 19th century. In Western Europe, they faced discrimination. For example, in Germany under the Holy Roman Empire, there were many laws legislating that gypsies, for example, who entered a town could be shot. There is a history in the 19th century of more informal forms of discrimination and persecution.


So, for instance, if a gypsy showed up in Italy, the assumption was that they could not be Italian. They were automatically excluded from Italian citizenship and were expelled out of the country. So this is - this has a long history. And as recently as a few weeks ago, we saw the French foreign minister claiming that Romanian and Bulgarian gypsies could not assimilate into French life.


BLOCK: We should mention, too, of course, that the Roma were a target for extermination by the Nazis during the Holocaust.


ILLUZZI: Yes, that is the obvious case. And one of the points that I think is important to make, however, is that there is a long legacy of this discrimination. This is not just something that happened during the Holocaust and the extermination of the Roma people. It didn't come out of nowhere. But the Holocaust is certainly the most obvious and traumatic example of discrimination against Roma populations.


BLOCK: Given the recent cases that we've been hearing, about these suspected cases of child abduction and trafficking among the Roma, would you be - would you expect that we'll be hearing more of these, that this is the kind of thing that ripples through the community?


ILLUZZI: Yes. I think one of the most disturbing aspects of this case is once it came up into the news and there's these images of this small, blonde, blue-eyed child in the news, that there is an immediate linkage to this discourse about disappeared children cases throughout Europe. It's incredibly problematic, and I do think that the tone with which this is being covered is going to put Roma at risk.


BLOCK: Professor Illuzzi, thanks so much for talking with us.


ILLUZZI: Thank you very much, Melissa.


BLOCK: Jennifer Illuzzi is assistant professor of history at Providence College in Rhode Island. Her forthcoming book is called "Gypsies in Germany and Italy 1861-1914."


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Source: http://www.npr.org/templates/story/story.php?storyId=240559705&ft=1&f=1004
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Thursday, October 24, 2013

Actress: Dancing with prince 'better than sex'




Myanmar opposition leader Aung San Suu Kyi , centre, stands with Britain's Prince Charles Camilla Duchess of Cornwall during a meeting at Clarence House, in London Wednesday Oct. 23, 2013. (AP Photo/Arthur Edwards/Pool)





LONDON (AP) — Actress Emma Thompson says dancing with Prince Charles is "better than sex."

Thompson makes the comment in a Time magazine feature on the 64-year-old heir to the British throne.

Charles tells the magazine he has had a lifelong desire to "heal and make things better."

The prince, who backs a host of charitable and environmental causes, said he feels it is his "duty to worry about everybody and their lives in this country, to try to find a way of improving things if I possibly can."

He also reveals that he recently staged a rehearsal to help teach his son, Prince William, how to host an investiture ceremony in which Britons receive knighthoods and other honors.

William presided over his first investiture at Buckingham Palace last week without any problems.

Source: http://news.yahoo.com/actress-dancing-prince-better-sex-190357708.html
Category: eric decker   Tomas Hertl   liberace   Joy Covey   Elmore Leonard  

A look at advances, complications for Saudi women

FILE - In this Thursday, May 10, 2012 file photo, a Saudi woman poses for photo inside the Qasr al-Bint tombs complex in the desert archaeological site of Madain Saleh, in Al Ula city, 1043 km (648 miles) northwest of the capital Riyadh, Saudi Arabia. It’s been a little more than two years since the last time women in Saudi Arabia campaigned for the right to drive. Since then, the ultraconservative kingdom has seen incremental but key reforms _ not exactly momentum, but at least cracks in the smothering restrictions on women that activists hope to pry open further as they call on women to get behind the wheel in a new campaign Saturday, Oct. 26, 2013. (AP Photo/Hassan Ammar, File)







FILE - In this Thursday, May 10, 2012 file photo, a Saudi woman poses for photo inside the Qasr al-Bint tombs complex in the desert archaeological site of Madain Saleh, in Al Ula city, 1043 km (648 miles) northwest of the capital Riyadh, Saudi Arabia. It’s been a little more than two years since the last time women in Saudi Arabia campaigned for the right to drive. Since then, the ultraconservative kingdom has seen incremental but key reforms _ not exactly momentum, but at least cracks in the smothering restrictions on women that activists hope to pry open further as they call on women to get behind the wheel in a new campaign Saturday, Oct. 26, 2013. (AP Photo/Hassan Ammar, File)







Saudi women reformers plan to flout a ban on driving Saturday. Here is a look at some of the milestones and roadblocks for women's rights in the ultraconservative kingdom since the last campaign to win women's right to drive in June 2011.

— King Abdullah grants women right to vote and run in the 2015 municipal elections. The decision is hailed as a breakthrough, but the local councils are toothless and operate in the shadow of provincial governments led by powerful members of the ruling Al Saud family.

— The king appoints 30 women to the top advisory body, the Shura Council. The body cannot legislate and its male-dominated chamber has so far not taken up a request by three female members to discuss the issue of allowing women to drive.

— In a first, Saudi Arabia sends two female athletes to the 2013 Olympics in London. But they were criticized by conservatives for performing sports in front of a mixed gender audience. Aspiring female athletes in the kingdom struggle to find access to training facilities.

— The government rolls out a law penalizing domestic abuse, including neglect. A state-backed advertisement shows a woman in a traditional black face veil with a bruised eye peering through, encouraging society to speak out against abuse. The law does not address the guardianship system that grants male family members authority over their female relatives, and often the abuser is their guardian. Two Saudi women activists who helped a Canadian mother allegedly abused by her Saudi husband were sentenced to 10 months in jail for "inciting a woman against her husband."

— A law on the books since 2006 is finally implemented, allowing women to work as sales' clerks in female apparel and lingerie stores. Saudi Arabia's most senior cleric, Sheik Abdul-Aziz Al Sheikh, spoke out against the Labor Ministry's decision in a sermon just before the law was applied, saying it contradicts Islamic law. The kingdom's religious establishment follows a strict interpretation of Islam known as Wahhabism.

— The Labor Ministry allows women to work in certain sectors without first obtaining their guardian's approval. Still, the decrees mandate that female workers not interact with men, reinforcing strict gender segregation, according to Human Rights Watch. Some private sector workplaces remain exempt from these decrees.

— Women are given licenses to practice law. The four women with permits will face conservative male judges who have wide discretion to remove a lawyer from a case before them.

— Private schools are officially allowed to hold sports activities for girls, and physical education is required as part of the curriculum. Sports centers around the country are almost entirely for men only, female gyms are costly and public schools have yet to implement physical education for girls.

— A ban on women riding bicycles and motorbikes is lifted. Females must be accompanied by a male guardian, usually a husband or son, and only ride in restricted areas.

— Official reports suggest women will be allowed to attend soccer matches in a new stadium in 2014. The women will be segregated from the men in sections for families.

Associated PressSource: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-10-24-ML-Saudi-Women-Driving-Glance/id-a208e43d8c7e4d8789ef9cd19c63db2b
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Dido Dazzles With Delicious Big Apple-Inspired Song! Feast Your Ears On NYC HERE!






Our angel returns!


And she comes bearing gifts!


It's been months since we last heard from Dido, but the brilliant Brit is preparing to release what we're sure will be a most glorious Greatest Hits album later this month and we couldn't be more thrilled!!


Even better, it includes a heavenly new song called NYC!


Ch-ch-check it out (above)!


AMAZEBALLZ! We adore it! We srsly want Dido's flawless new track to move into our ears and live there forever!! No rental application or credit check required!!


Look for Dido's Greatest Hits — which includes the Eminem rib-tickler Stan — on November 25th.


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Source: http://perezhilton.com/2013-10-24-dido-nyc-new-track-greatest-hits-listen-here
Tags: Tomas Hertl   Victoria Duval   Claude Debussy   amc   Erbie Bowser  

Study: Metformin for breast cancer less effective at higher glucose concentrations

Study: Metformin for breast cancer less effective at higher glucose concentrations


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PUBLIC RELEASE DATE:

23-Oct-2013



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Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver





A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome. The study also showed that patients with high glucose may require higher doses of the drug metformin to achieve the same anti-cancer activity as patients with normal glucose levels.


Metformin, the most common first-line drug in the treatment of type-2 diabetes, has been shown in previous studies to reduce breast cancer risk, improve survival, and increase the effectiveness of chemotherapy. Numerous Phase III clinical trials are currently evaluating the benefits and best uses of metformin in breast cancer patients.


"We show that metformin works differently in high- compared to low-glucose conditions. Not only does it require a higher concentration of metformin to be active in high-glucose conditions, but we report that the drug regulates different genes within cancer cells at high as compared to normal glucose levels," says Ann Thor, MD, CU Cancer Center investigator, Todd Professor of Pathology at the University of Colorado School of Medicine, and the study's principal investigator.


The study evaluated the effects of metformin on 17 breast cancer cell lines representing each of the molecular subtypes of the disease, at varying glucose levels.

"Commonly, lab studies of metformin are performed with very high glucose concentrations about 17 millimols of glucose per liter. But the average glucose level in healthy humans is only about one third of that dose about 5 millimols per liter. And individuals with diabetes may have glucose at 10 millimols per liter. We wanted to study metformin activity under these conditions," Thor says.


So the question was this: how would metformin perform in breast cancer cells grown at more realistic, human levels of glucose?


"Results show that when you drop glucose down to human levels, metformin has an even bigger effect at standard doses. When glucose is high you need more metformin to achieve the same results," Thor says.


Thor also points out that skeptics of metformin treatment for cancer in general or breast cancer in particular frequently point to the high concentrations of metformin needed to create results in the laboratory.


"Our data helps to explain why higher doses of metformin are required to obtain anti-cancer effects when cancer cells are grown in the lab, as compared to its use in humans," Thor says.


Interestingly, "it wasn't simply that the metformin effectiveness went up as glucose came down, but that entirely new mechanisms of action were present at lower glucose levels," Thor says.


Specifically, Thor and colleagues used RNA expression arrays to discover which genes were affected by metformin at high and low glucose concentrations. At high glucose concentrations, metformin primarily affected genes involved in metabolic processes and cell proliferation; at low glucose concentrations, metformin affected genes controlling cellular process and programmed cell death.


In addition to affecting the growth of breast cancer cells, Thor and colleagues show the drug decreases the ability of breast cancer cells to move within the body a task necessary for the spread of the disease to other sites.


"An extension of this data implies that in breast cancer patients with diabetes or metabolic syndrome, metformin may less effective at the standard dose. To be effective, doctors may have to first explore glucose control or may have to use a higher dose of metformin," Thor says.



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Study: Metformin for breast cancer less effective at higher glucose concentrations


[ Back to EurekAlert! ]

PUBLIC RELEASE DATE:

23-Oct-2013



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]


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Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver





A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome. The study also showed that patients with high glucose may require higher doses of the drug metformin to achieve the same anti-cancer activity as patients with normal glucose levels.


Metformin, the most common first-line drug in the treatment of type-2 diabetes, has been shown in previous studies to reduce breast cancer risk, improve survival, and increase the effectiveness of chemotherapy. Numerous Phase III clinical trials are currently evaluating the benefits and best uses of metformin in breast cancer patients.


"We show that metformin works differently in high- compared to low-glucose conditions. Not only does it require a higher concentration of metformin to be active in high-glucose conditions, but we report that the drug regulates different genes within cancer cells at high as compared to normal glucose levels," says Ann Thor, MD, CU Cancer Center investigator, Todd Professor of Pathology at the University of Colorado School of Medicine, and the study's principal investigator.


The study evaluated the effects of metformin on 17 breast cancer cell lines representing each of the molecular subtypes of the disease, at varying glucose levels.

"Commonly, lab studies of metformin are performed with very high glucose concentrations about 17 millimols of glucose per liter. But the average glucose level in healthy humans is only about one third of that dose about 5 millimols per liter. And individuals with diabetes may have glucose at 10 millimols per liter. We wanted to study metformin activity under these conditions," Thor says.


So the question was this: how would metformin perform in breast cancer cells grown at more realistic, human levels of glucose?


"Results show that when you drop glucose down to human levels, metformin has an even bigger effect at standard doses. When glucose is high you need more metformin to achieve the same results," Thor says.


Thor also points out that skeptics of metformin treatment for cancer in general or breast cancer in particular frequently point to the high concentrations of metformin needed to create results in the laboratory.


"Our data helps to explain why higher doses of metformin are required to obtain anti-cancer effects when cancer cells are grown in the lab, as compared to its use in humans," Thor says.


Interestingly, "it wasn't simply that the metformin effectiveness went up as glucose came down, but that entirely new mechanisms of action were present at lower glucose levels," Thor says.


Specifically, Thor and colleagues used RNA expression arrays to discover which genes were affected by metformin at high and low glucose concentrations. At high glucose concentrations, metformin primarily affected genes involved in metabolic processes and cell proliferation; at low glucose concentrations, metformin affected genes controlling cellular process and programmed cell death.


In addition to affecting the growth of breast cancer cells, Thor and colleagues show the drug decreases the ability of breast cancer cells to move within the body a task necessary for the spread of the disease to other sites.


"An extension of this data implies that in breast cancer patients with diabetes or metabolic syndrome, metformin may less effective at the standard dose. To be effective, doctors may have to first explore glucose control or may have to use a higher dose of metformin," Thor says.



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.




Source: http://www.eurekalert.org/pub_releases/2013-10/uocd-smf102313.php
Category: kris jenner   Electric Zoo  

The Obamacare Tech Mess? It's A Familiar Government Story





In this Oct. 11 computer frame grab, a HealthCare.gov website message is displayed.



Uncredited/AP


In this Oct. 11 computer frame grab, a HealthCare.gov website message is displayed.


Uncredited/AP


By this point, it's all but a universally acknowledged truth that the launch of the HealthCare.gov website has been a failure.


That's bad news for President Obama and his health care law. But it's not exceptional when it comes to big government software programs and platforms.


Earlier this year, California ended a contract to modernize its payroll system, an effort that had eaten up 10 years and $250 million and gotten essentially nowhere. Colorado has had a number of high-profile embarrassments when upgrades to its revenue systems caused residents tax refund and car title problems, while Florida legislators last year scuttled a $70 million attempt to unify the state's email systems.


In fact, governments at every level — but particularly states and the feds — have suffered expensive, embarrassing flops when it came time to roll out new information technology (IT) projects.


"The bigger the system, the harder it is, because there are more variables," says Steve Kolodney, a former chief information officer for the state of Washington.


It isn't just size.


Private sector companies generate plenty of software flops, too. But the way governments typically manage computer projects — with diffuse authority, penny pinching and a deadly combination of delays and rigid deadlines — they're especially prone to producing disappointment.


No One Really In Charge


It doesn't seem like there should be any great trick to designing new systems. We've all become accustomed to using our computers or phones to easily order new barbecue sets along with a dozen out-of-print books, or to stream old sitcoms all weekend.


So why is it such a trick for government to get people signed up for health insurance, or make appointments at the Department of Motor Vehicles?


There are a bunch of reasons. The first problem is that top-ranking government officials often expect these things to be easy. They come up with some application they want started up and then expect the IT guys and their vendors to make it happen.


It's like having no knowledge of what goes on under the hood, and then pulling into the dealership and asking them to design an entirely new car.


"They proudly announce that they don't understand the technology — 'my 14-year-old knows more than I do,' which is a moronic statement," says Gopal Kapur, founder of the Center for Project Management in California.


Legislators and agency heads may not know anything about lines of code, but that doesn't keep them from second-guessing the tech folks. They tend to view IT as a drain on resources and wonder why they have to keep buying new versions of software to keep up.


When it comes to government projects, Kapur says, people know they have to spend money in a given year, because funding may dry up the following year. Planning for upgrades over, say, a three-year period just doesn't happen the way it should.


"Companies don't fall apart because a new CEO comes," he says. "If you go to a state, nobody does anything for a year before the governor's going to change, and then the year after nobody does anything because they don't know what the governor wants."


Keeping Up With The Times


Big government projects can take years to build, which means the world of technology will have changed dramatically since a given project began.


There's just been a new iPad released, for instance, but think about how important tablets have become in just the past few years. You wouldn't want to design a user interface today that didn't take into account mobile computing.


But governments typically don't budget for the need to overhaul entire project designs along the way. And, because of strict procurement rules, the IT staff may not be able to buy new products it needs, sometimes for more than a year at a stretch.


Meanwhile, policymakers keep asking for new features. There may be changes in law that have to be incorporated within a website. The budget deal that reopened the government this month, for instance, included stricter income verification requirements for people signing up for coverage under the health care law.


That's not why HealthCare.gov isn't working, but things like that happen all the time. It's as if a developer had to start construction of an office tower using an incomplete set of blueprints and then was told at the last minute to add another elevator shaft and a couple of bathrooms per floor.


Some people in the IT world like to argue it's never the technology that's at fault, it's the management.


"Good governance, not superior technical chops or ready access to alpha geeks, is how you build complex systems that deliver reliable and resilient value for money," Michael Schrage, a research fellow at the MIT Center for Digital Business, wrote in a Harvard Business Review blog post Tuesday.


Getting Ready In Time


There's no end to software snafus in the private sector. A filing with the Securities and Exchange Commission just last week outlined how a software bug led trading firm Knight Capital to lose $172,000 a second for 45 minutes.


Still, governments demand perfection in a way that private companies generally do not. Obama compared the health care website's problems to Apple, and that company's problems with its maps app show how even the best-run brands can run into trouble.


A better comparison might have been with Google, however, which releases beta versions of programs it knows will have bugs. That company relies on crowdsourcing to find and help fix any issues.


"That's not the model in government," says Doug Robinson, executive director of the National Association of State Chief Information Officers, or NASCIO.


"In government, you want to release something that's absolutely rock-solid perfect the day you release it to the market," Robinson says. "That might not be possible."


Knowing a big release date is coming — say, Oct. 1 for the exchanges at HealthCare.gov to go live — doesn't lead to new levels of quality control. Instead, problems are patched and may be overlooked by agency heads or other managers who just want to get the thing up and running.


A new website might have all the latest and zippiest features, but if it's having to talk to antiquated systems — as is often the case with back-end government operations, which offer differ wildly by agency — it still may not work.


"States certainly have had their fair share of projects that have failed or at least underperformed after tens or hundreds of millions have been spent," Robinson says.


Check The Vital Signs


To combat some of these problems, states such as California and Indiana are now making public what they call the "vital signs" of every major project, allowing politicians and the public to keep track of how every aspect of development is proceeding along the way.


It's like when the police release details about a case, but not necessarily every scrap such as the name of the victim, says Kapur, in hopes the public can offer information that might help the case.


The government itself, however, is ultimately responsible. That's why it was important that the president himself came out on Monday and took his lumps about HealthCare.gov's failures, Kapur says.


Often, it's the IT people who are forced to face the cameras. They have to explain why things aren't working, but typically lack the power to make changes that can turn a project around.


"They can find the problems and report the problems, but they don't have the political or administrative authority to change what is causing the problems," Kapur says.


Source: http://www.npr.org/blogs/alltechconsidered/2013/10/24/240247394/the-obamacare-tech-mess-its-a-familiar-government-story?ft=1&f=1019
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iPad Air hands-on (update: video)

It's the iPad that's so light, they needed a whole new name. At first glance, there's not a heck of a lot new about the Air (though the more discerning amongst you may well notice the new dual-mics at top). There's a brushed metal backing (which is awfully shiny under these bright lights), a power ...


Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/K-eWTlTY9YU/
Category: Rebel Wilson   Chobani Recall   Solheim Cup 2013   Myla Sinanaj   Breaking Bad Season 6  

Facebook Users Don't 'Like' This: Status Update Error Messages



If you tried to post a status update on Facebook or "like" someone else's Monday morning, you probably got a message like this:


"There was a problem updating your status. Please try again later."


You are not alone. The Miami Herald reports:




"Facebook users are reporting trouble logging in and posting updates Monday morning.


"Some users are seeing a 'temporary disruption of service' warning.


" 'Servers are down,' one user posted on Twitter.


" 'So, it's not just me,' posted another."





The site "Downrightnow" said, indeed (as of 10:40 a.m. ET) that Facebook was having some problems.


And here's an example of the sort of reaction trending on the rival Twitter under the hashtags #GetWellSoonFacebook and #RIPFacebook:


The Two-Way has reached out to Facebook for comment, but we haven't heard back yet.


Source: http://www.npr.org/blogs/thetwo-way/2013/10/21/239085415/facebook-users-dont-like-this-status-update-error-messages?ft=1&f=1019
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Obama, Pakistani PM meet amid easing tensions

Pakistan's Prime Minister Nawaz Sharif arrives at the White House in Washington, Wednesday, Oct. 23, 2013, for his meeting with President Barack Obama. The White House said that the leaders would discus, trade, energy, economic development, and efforts to address violent extremism. (AP Photo/Charles Dharapak)







Pakistan's Prime Minister Nawaz Sharif arrives at the White House in Washington, Wednesday, Oct. 23, 2013, for his meeting with President Barack Obama. The White House said that the leaders would discus, trade, energy, economic development, and efforts to address violent extremism. (AP Photo/Charles Dharapak)







An armored sports utility vehicle carrying Pakistan's Prime Minister Nawaz Sharif drives past a military honor cordon as he arrives at the White House in Washington, Wednesday, Oct. 23, 2013, for his meeting with President Barack Obama. The White House said that the leaders would discus, trade, energy, economic development, and efforts to address violent extremism. (AP Photo/Charles Dharapak)







Supporters of Pakistan's Islamist party Pasban, rally against US drone strikes on hideouts of militants in the country's tribal areas, in Karachi, Pakistan, Wednesday, Oct. 23, 2013. Pakistan's Prime Minister Nawaz Sharif who is scheduled to meet President Barack Obama, urged the United States to end drone attacks, saying that the unmanned strikes represented a "major irritant" in relations. (AP Photo/Shakil Adil)







(AP) — In the rocky relationship between the U.S. and Pakistan, the mere fact that President Barack Obama and Pakistani Prime Minister Nawaz Sharif are sitting down together at the White House is seen as a sign of progress.

Few breakthroughs were expected on the numerous hot-button issues on their agenda Wednesday, including American drone strikes and Pakistan's alleged support for the Taliban. But officials in both countries are hoping to scale back tensions that escalated after the 2011 U.S. strike within Pakistan that killed Osama bin Laden and last year's accidental killing of two dozen Pakistani troops in an American airstrike along the Afghan border.

"We want to find ways for our countries to cooperate, even as we have differences on some issues, and we want to make sure that the trajectory of this relationship is a positive one," White House spokesman Jay Carney said.

Sharif was welcomed to the White House Wednesday afternoon by a military honor guard lining the driveway leading to the West Wing. Vice President Joe Biden also held a breakfast meeting with Sharif and first lady Michelle Obama hosted a tea and poetry recital for the prime minister's wife.

Obama and Sharif talked on the phone earlier this year, but they have never met in person. Sharif, who served two earlier stints as Pakistan's prime minister, has held face-to-face talks with Secretary of State John Kerry and was scheduled to meet with other top U.S. officials while in Washington this week.

The prime minister's visit to the White House comes one day after Amnesty International released a report providing new details about the alleged victims of U.S. drone attacks in Pakistan, one of them a 68-year-old grandmother hit while farming with her grandchildren. In Pakistan, there is widespread belief that American drone strikes kill large numbers of civilians and Sharif is expected to raise the issue with Obama.

The White House responded to the Amnesty report by defending the drone program, with Carney saying U.S. counterterrorism operations "are precise, they are lawful and they are effective."

Also on the agenda for Wednesday's meeting will be Obama's looming decision on whether to keep any American troops in Afghanistan after the war there formally concludes at the end of next year. Ahead of the U.S. withdrawal, the U.S. is seeking to push through a peace deal with the Taliban and Afghan government.

Pakistan is seen as key to this process because of its historical connection to the Taliban. It helped the group grab power in Afghanistan in 1996 and is widely believed to have maintained ties as a hedge against neighbor and nuclear rival India — an allegation denied by Islamabad.

Ahead of his trip to the U.S., Sharif said he planned to ask Obama for American intervention in resolving the dispute between Pakistan and India in Kashmir.

On Wednesday, India accused Pakistani troops of firing guns and mortars on at least 50 Indian border posts overnight in Kashmir. Indian troops returned fire, but one Indian guard was killed and six were injured by a shell fired at the Arnia post in the Jammu region, he said.

Indian Foreign Minister Salman Khurshid rejected the idea of U.S. involvement, saying Kashmir was a "bilateral issue between India and Pakistan."

___

Follow Julie Pace at http://twitter.com/jpaceDC

Associated PressSource: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-10-23-United%20States-Pakistan/id-9066d339e89b44e8a091136ab3129ad8
Tags: Alice Munro   Jake Locker   Ryne Sandberg   Desiree And Chris   Spain train crash  

Why Making Mavericks Free Makes Perfect Sense

Why Making Mavericks Free Makes Perfect Sense

Yesterday, Apple not only released its OS X Mavericks operating system, it also announced that it would be free. That's great! For you, for Apple, and for the future of computing.

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Source: http://feeds.gawker.com/~r/gizmodo/full/~3/ITNtJGm_2-w/why-making-mavericks-free-makes-perfect-sense-1450804106
Category: brandon marshall   Bobby Cannavale   jim parsons   Nick Pasquale   Colorado flooding